The early change disrupted the visitors but they played with greater purpose after the break in an enthralling affair.
31 min: Perhaps unsurprisingly, Santos make an early change, bringing on former Manchester City sulk Elano for Danilo.
On a muggy Melbourne night Djokovic went for a very early change of shirt, to black, after only half an hour.
Simeone was forced into an early change when Diego Costa's hamstring problem flared up, putting Atlético on the back foot despite their early lead.
Photograph: Tony Gentile/Reuters Updated at 1.36pm GMT 1.30pm GMT 44 mins Italy make a very early change with Orquera being hooked for Allan.
Swansea were forced to make an early change when Pablo Hernández went off injured and the substitution worked to their immediate advantage.
In a sign of early change on the ground, Hamas's television broadcasts were beamed for the first time into the West Bank, and Palestinian Authority broadcasts into Gaza.
Stoke had for the most part been comfortably in control in the first half, despite an injury to Peter Crouch forcing them into an early change.
And Strachan felt that early change affected his side.
Both sides were forced into an early change.
Thus, early change after BTX injection on the masseter muscle is important to understand the clinical application of BTX.
