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However, genetic data is relatively lacking after this earliest transition period, when societies had fully adapted to new agrarian lifestyles specific to their local environment.
Furthermore, gene network analysis revealed that clusterin appeared to serve as a link between the overall decreased bioenergetic metabolism and increased amyloid dyshomeostasis associated with the earliest transition in female brains.
Traces of this earliest transition, may, moreover, be sparse, given the timescale of the divergence.
The earliest transition to bird-pollination syndrome was reconstructed on the stem leading to the Leptosema clade.
These findings suggest a role for Tcf15 in manipulating and monitoring the earliest transition from pluripotency toward lineage commitment.
CK18 intermediate filaments are completely lost around birth, thereby signaling the earliest transition of SCs to a mature state.
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We used the dated phylogenies to infer the timing of the earliest transitions between pollination syndromes.
The earliest transitions overlap with the early diversification of Australian honeyeaters – the major lineage of pollinating birds in Australia.
We estimated the earliest transitions from bee- to bird-pollination syndrome occurred between 30.8 Ma and 10.4 Ma.
The earliest transitions to bird-pollination syndrome, which we estimated to have occurred ca. 10.4-30.8 Ma (cpDNA) and 7.6-29.6 Ma (ITS), mostly overlap with the radiation of honeyeaters.
One of the earliest transitions in the subspace domain to signal the collective fragmentation of the mitochondria is the initiation of programmed cell death 42.
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