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Classically in the literature one of the earliest studies reported was on visual contribution to postural control [9], primarily because vision is easy to manipulate and by the fact that when the eyes are closed, stability decreases.
Weidner et al (1991), in one of the earliest studies, reported a significant correlation between the degrees of IMD at the vascular hot spot with the probability of metastasis in a series of 49 patients with invasive breast cancer.
One of the earliest studies reported an association between major depression in AD at baseline and 5-HT (2A) and 5-HT (2C) receptor polymorphisms, with CC carriers of the 5-HT (2A) C102 allele five times more likely than heterozygotes and 5-HT (2C) Ser allele carriers 12 times more likely than 5-HT (2C) Cys allele carriers to develop depression [ 29].
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Earlier studies reported that shock wave therapy was beneficial.
Two earlier studies reported that golden jackals found in Africa are more closely related to grey wolves than to the golden jackals found in Eurasia (doi 10.1371/journal.pone.0016385 & doi 10.1371/journal.pone.0042740).0042740
Early studies reported increased serum levels of anti-hCMV antibodies in SSc patients [59].
Earlier studies reported that the Na+ channel blocker TTX was not able to consistently inhibit CSD [67 69].
Earlier studies reported the heterogeneity in SVF and great variability in the percentages of different subsets [35, 36].
Earlier studies reported that disturbance generally had the greatest impact on biological properties, including symbiotic fungal populations [39, 40].
Early studies reported comparative results of functional outcomes between robot-assisted (RARP) and retropubic radical prostatectomy (RRP).
Earlier studies reported sympathetic ophthalmia following trauma to be most likely; however, more recent studies report injury from ocular surgery to be the more common cause [55].
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