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Although high RNA is the earliest predictor of clinical progression after HIV seroconversion, for populations of treatment-naïve patients during stable infection or with unknown date of seroconversion, CD4 surpasses RNA as a prognostic indicator and screening tool to select patients in need of ART.
Week 24 has been proposed as the next earliest predictor of outcomes [ 21].
Whole-body insulin resistance is the earliest predictor of type 2 diabetes onset, and this mainly reflects muscle insulin resistance (26).
The earliest predictor of the development of type 2 diabetes is low insulin sensitivity in skeletal muscle, but it is important to recognize that this is not a distinct abnormality but rather part of the wide range expressed in the population.
Some data indicate that clonal restriction of the HIV-specific CD8+ T cell response is the earliest predictor of rapid disease progression, suggesting that the initial dynamics of CD8+ T cell-mediated suppression of viral replication versus viral dissemination, diversification and immune destruction play a major role in determining the steady-state parameters of chronic infection [ 17, 29].
Similar(55)
Such communication difficulties meant that a usual early predictor of African famine, the plummeting of livestock prices, was missed.
Retailers typically do some of their biggest business during the back-to-school shopping period, also considered to be an early predictor of the holiday shopping season.
Google Flu Trends tracks flu-related search terms as an early predictor of flu outbreaks.
Urinary [TIMP-2]*[IGFBP7] may be considered as early predictor of AKI after CABG surgery.
This information in turn, can be used as an even earlier predictor for future crowd characteristics.
An early predictor of optimal pain relief was sensory block of the inner thigh.
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