Sentence examples for earliest features in from inspiring English sources

Microvascular damage is one of the earliest features in the pathogenesis of SSc leading to a progressive loss of capillaries [ 12].

Leucostasis is one of the earliest features in murine diabetic retina and can be detected from as early as 1 week after diabetes induction, persisting for at least 3 months [ 23].

Peter A Jones (USC/Norris Comprehensive Cancer Center, Los Angeles, CA, USA) reviewed evidence that aberrant methylation patterns are one of the most diagnostic and earliest features in cell transformation, and presented his own work employing a methylation-sensitive PCR technique to scan the genome in a bladder tumorigenic cell line.

Apple slowly restored many earlier features in the intervening years.

Fibrin deposition and hyaline membrane formation are considered important early features in diffuse alveolar damage, the hallmark of ARDS [1, 10 12].

In addition, the role of oxidative stress has been evaluated in experimental models of acute pancreatitis [43] and it should be emphasized that oxidative stress and excessive ROS generation are early features in AP and consequently a difficult target for clinical prophylaxis to prevent a severe course of the disease.

For example, atrophy in the hippocampal formation is an early feature in the progression of Alzheimer disease, with patients demonstrating impairments in spatial orientation and navigation.

Prof Tony Charman, Centre for Research in Autism and Education at the Institute of Education, said: "Differences in the use of eye gaze to regulate social interaction are already a well-recognised early feature in many children with autism from the second year of life.

Charlie is engaged to Sophia, a woman earlier featured in his dream.

Our hypothesis was that increased postprandial NEFA appearance and oxidation may be an early feature in non-diabetic subjects at high risk of developing T2D.

We hypothesized that miR-155 up-regulation may be an early feature in gba1 −/−.