Sentence examples for earliest changes are from inspiring English sources

The earliest changes are synaptic in nature and are detectable in particularly vulnerable white matter pathways such as the perforant path.

Plain radiographs are normal in the acute stages and the earliest changes are only seen after several weeks.

Thus treatments that avoid or delay these irreversible consequences by targeting the earliest changes are urgently needed.

The earliest changes were seen in Hanley and Burslem when in 1813 the Hanley Market Act (53 Geo. 3 c.cxv) gave statutory control of Hanley market to a board of trustees outside manorial control.

As in the response to N-addition, the earliest changes were dominated by the increase in transcripts for PPR proteins that in the P study were measurable as early as 1 h following P-addition.

It's the nature of entitlement programs, especially Social Security and Medicare, that the earlier changes are made, the less painful they have to be.

The most profound and early changes are likely to occur in the 13 federal appeals courts, the level just below the Supreme Court, where 25 of the 179 seats are now vacant.

When an inflorescence forms, early changes are generally comparable to that for the single flower with one major difference axillary primordia emerge that either become floral meristems or develop as secondary inflorescence branches.

The non-linear relation between RI and VT, however, does indicate that for RI it might be the case that early changes are not readily detected.

Early changes are better delineated on MRI, with loss of homogenous high signal on T2-weighted images or rupture of the fibrous capsule [22].

Some of the early changes are thought to act as local "tags", allowing only sites that are active in the early phase to utilize newly synthesized gene products from the nucleus during the late phase [13], [14].