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Earliest case reports date back to the 1800s [ 3].
This description likely stems from the earliest case reports of ReA, which largely consisted of STD-related cases.
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Patients with the earliest case report date within a cluster were regarded as index cases.
Early case reports eventually multiplied into trials that have treated about 350 leukemia and lymphoma patients.
Responding to the early case reports, the ACNP convened its first Task Force to study the matter in 1993 (Mann et al, 1993).
In these early case reports and scientific studies, physicians and researchers declared that patients should have liver function tests during anti-androgen therapy, but didn't specify how often.
Early case reports emphasized regression of cancers during naturally acquired virus infections, providing the basis for clinical trials where body fluids containing human or animal viruses were used to transmit infections to cancer patients.
This review details evidence linking the use of PPI therapy to the development of kidney disease, including early case reports of acute interstitial nephritis and subsequent large observational studies of AKI, CKD, and ESRD.
In this chapter I review the history of HNPCC, from early case reports, to more systematic clinical information and clinical criteria, and finally to the discovery of the MMR genes themselves in 1993, including the key feature of microsatellite instability.
CONCLUSIONS: These findings do not support earlier case reports of outright myocardial necrosis after terbutaline tocolysis in human infants.
Despite the limitations in data quality, we also included early case reports and clinical observations to add clinical context.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com