Sentence examples for earliest b from inspiring English sources

The generation of the earliest B cell progenitors critically depends on the transcription factors E2A and EBF.

Germ-line deletion of Bcl11a causes neonatal lethality and an absence of B cells at the earliest B cell development stages [ 105, 106].

CD19 is the earliest B specific protein expressed on B cells and becomes lost as the activated B cell matures into a plasma cell.

These findings demonstrate that the myeloid propensity of FLT3-ITDs results from FLT3-ITD introducing a myeloid bias in multipotent lymphomyeloid progenitors as well as in the earliest B and T lymphoid progenitors.

Using a Pu1-YFP reporter, we demonstrated that Flt3-ITDs upregulate Pu1 expression in MPPs and the earliest B lymphoid progenitors, paralleled by increased expression of Pu1 target genes in MPPs.

The earliest B cell progenitors are responsive to the stimulatory action of the chemokine CXCL12 (SDF-1) [ 6, 7] produced by BM stromal cells [ 8], acting via the CXCR4 receptor on the pro-B cells [ 9, 10].

The CD20 antigen is expressed by the majority of cells in the B-lymphocyte lineage, but not by haematopoietic stem cells, the earliest B-cell precursors (pro-B cells) or terminally differentiated plasmablasts and plasma cells.

The earliest B-lineage restricted progenitors (pro-B) were sorted based on a B220+ CD43+ CD19+ IgM- surface phenotype while pre-B cells were defined as B220+ CD43- CD19+ IgM-cells from mouse bone marrow and mature B-cells as CD19+ IgM+ cells from mouse spleen [ 33].

But the early b gets the w, and that b is Joel Bass, of Englewood, CO.

Early (b) and late (c) phases of the FA demonstrating early hyperfluorescence and late staining.

The mechanisms underlying the silencing of alternative fate potentials in very early B cell precursors remain unclear.