Sentence examples for earliest adverse from inspiring English sources

These two environmental factors may be among the earliest adverse life experiences that "programs" or (re-programs) the physiological, neuroendocrine and metabolic adaptations that underlie early human brain development, setting a course of health or illness that may last a life time.

Maladaptive alterations of cardiac metabolism plays a pivotal role in the development of diabetic cardiomyopathy [1] and abnormal regulation of carbohydrate and fatty acid metabolism has been well-characterized as one of the earliest adverse manifestation of diabetes on cardiac myocyte function [1], [2].

The earliest adverse effect of Cd is an impairment of the tubular function, resulting in an increased urinary excretion of low-molecular-weight (LMW) proteins such as retinol-binding protein.

The Vancouver Winter Games in 2010 suffered similar early adverse publicity before winning over the public and competitors alike.

Abciximab during primary PCI is associated with fewer early adverse outcomes, likely contributing to offset its cost.

Early adverse life events (EALEs), such as the death of a parent, are well-established risk factors for MDD.

To examine antivenom use, premedication, early adverse reactions and patient outcomes after snake bite in rural Papua New Guinea.

Maternal deprivation (MD) has been developed to study the effects of early adverse experiences on behaviour and neurobiology.

A cTnI level of 0.1 2.0 ng mL−1 indicates to an unstable angina and other heart disorder, whereas a level greater than 2.0 ng mL−1 places a patient in high-risk category for early adverse outcomes [24, 25].

Thus, when designing novel nanotoxicity testing methods, biomarkers can be a primary tool in assessing the health effects caused by nanoparticle exposure as they can be used to detect early adverse effects.

From these early adverse experiences, I learned the most important thing that a child needs.