As noted earlier, indicators or indices are often presented as ranks, which are ordinal rather than interval or ratio quantities despite the use of integers.
Taken together, these statistics indicate that there is an urgent need for earlier indicators of organ injury and susceptibility and molecular based indicators to improve return to duty decisions [ 7].
There had been other, earlier indicators: on the night of Obama's re-election in November 2012, an exploratory political action committee was established, called Ready For Hillary, made up of strategists and close friends.
Some earlier indicators will be whether the family visits are accomplished this summer, how plans for Kim Jong Il's visit to Seoul proceed, and whether arrangements can be worked out for a joint Korean team in the World Cup soccer competition in 2002.
We were unable to use earlier indicators for this group, e.g. MMT at 6 yrs, because many group C patients were not diagnosed at this age, due to less severe myopathy and longer diagnosis delay (usually >4 yrs).
In moving from the first to second generation HC-QIs, two types of earlier indicators were dropped.
Furthermore, profiling a range of potential biomarkers may provide more sensitive or earlier indicators of pathological change.
More data on incidence and reversibility, but moreover earlier indicators of cardiac damage, might in the future enable the necessary level of surveillance to be individualised.
Taking type 2 diabetes, for example, though some clinical phenotypes such as obesity and impaired glucose tolerance are confirmed to be risk factors for the disease, the genetic information can be detected as earlier indicators for prevention and therapy.
There are earlier indicators of hepatocarcinogenic potential which include increased liver weight, evidence of cytotoxicity, enzyme induction and CAR agonist activity which are used to aid dose setting for long term bioassays and in estimating risk.
