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Despite being proclaimed a goal of Muslim pilgrimage, the city lost some of its earlier importance when the caliphate was moved from Damascus to Baghdad by the ʿAbbāsids in the mid-8th century.
As stated earlier, importance of IL-7 in naïve T cells survival has been documented [44].
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It has been shown that IFN-γ is important for Plasmodium clearance in the liver [22], in addition to its early importance for malaria clinical immunity [23].
The community derived its early importance from its position at the river crossing.
A fulling mill recorded in 1311 indicates the early importance of the manufacture of wool products.
After a period of complete abandonment, it was reoccupied in the Middle Ages, but it never regained its early importance.
Poetry magazine's own origins, in 1912, and early importance owe much to its association with High Modernism, including the work of T. S. Eliot and Ezra Pound.
First mentioned in 1097, Sandomierz gained early importance because of its geographic position astride the trade route between the Baltic and Black seas and Ruthenia.
Although few traces of the ancient Venta Belgarum remain, its central position in the Roman road system points to its early importance.
Gainsborough's early importance as a Saxon settlement was augmented when it became a military centre under the Danes (9th 11th century).
The early importance of Magadha may be explained by its strategic position in the Ganges (Ganga) River valley, enabling it to control communication and trade on the river.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com