Sentence examples for earlier implicated in from inspiring English sources

Pemetrexed, which has been earlier implicated in treatment of lung cancer, also exhibited a good binding affinity (− 32.76 .The residues which played a crucial role in the formation of strong H bonds are Ser102, Gly101, Arg243, Lys360, Asn361 and Lys 237.

A total of 143 women with RSA and 150 controls were sequenced for all the 8 exons looking for the above 3 linked SNPs of the PR gene earlier implicated in the RSA, as well as for any new SNPs that may be possibly found in the Indian population.

Reviewer #2: This paper addresses how the β-catenin protein, earlier implicated in neuro-muscular junction (NMJ) formation, operates at the molecular level.

TbUGP contains all of the crucial amino acids that were earlier implicated in catalysis or SB of UGPs from other eukaryotic species (Chang et al. 1996; Duggleby et al. 1996; McCoy et al. 2007).

By homology searches against a bacteriophage protein that oxidizes thymine in DNA, Tahiliani et al. [ 8] discovered three proteins, Ten-eleven translocation 1 3 (TET1-3), in mammalian genomes as candidate 5mC oxidases and confirmed such activity for TET1, a gene/protein earlier implicated in a translocation in a myeloid leukemia patient [ 9].

But the prosecutors said they did not have enough evidence to charge Chechnya's leader, Ramzan A. Kadyrov, who had earlier been implicated in the crime.

The predicted Sp1 site in the Vdac1 gene was of special interest since aberrant Sp1 mediated interaction has earlier been implicated in Huntington's disease mechanism [11].

Auxin related gene family has earlier been implicated in mediating auxin signaling extensively and controlling almost all the processes from embryogenesis to flowering [17].

It is noteworthy that PGL has earlier been implicated in optimal mitochondrial functions and maintenance of yeast susceptibility to azole antifungals [36].

As one of the earliest actors implicated in the phone hacking scandal, Mulcaire holds key information in the investigation of News Corp. and News of the World.

Nevertheless, few studies until recently have devoted attention to environmental compounds that could directly influence early changes implicated in the origin of new characters.