Sentence examples for each with a modest from inspiring English sources

The former postulates that complex phenotypes result from the cumulative effects of a number of common variants, each with a modest effect size and relatively low penetrance.

The "common-disease common-variant" hypothesis proposes that these diseases arise from many common DNA variants, each with a modest influence on disease risk.

TS is a heritable, complex genetic disorder where multiple genes, each with a modest effect, are postulated to interact with unknown environmental factors to produce the phenotype [ 5, 6].

The most likely reason for this phenomenon is the same as that described above for environmental epidemiology: (nearly) all of the high-risk genes have been identified, and the unexplained genetic susceptibility to cancer is likely because of a large number of variants, each with a modest effect on cancer risk.

They return again the week after and the week after that, each time with a modest offering of interest, and each time incrementally building a relationship of familiarity and trust.

There is a strong but complex genetic component to SLE susceptibility, whereby many polymorphisms each with a small or modest effect contribute to disease susceptibility.

Unlike more classic hereditary conditions -- such as Huntington's disease or cystic fibrosis -- that stem from mutations in a single gene with a dramatic effect, these complex and common diseases are often influenced by many genes, each with just a modest effect.

This also applies to several other risk alleles, including PTPN22*620W [ 5], each with only a modest effect on RA risk, whereas reports for the autoantibody-negative RA subset are sparse [ 6].

Each DVD set comes with a modest bonus, a minidocumentary in which singers, directors and conductors are shown in rehearsal and give brief observations about the opera at hand.

The two other movies premiering this weekend, the Jennifer Aniston rom-com "Wanderlust" and the Amanda Seyfried thriller"Gone," are each expected to open with a modest sum of less than $10 million.

Each of these loci is associated with a modest risk and, although fairly common they contribute very little to the overall burden of CRC.