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Table 1 also shows measures of survival of patients in each two year sub-cohort.
For physical activity and alcohol intake, we used the cumulative average from all available questionnaires up to the start of each two year follow-up.
Thus we performed lag analyses using physical activity data collected at least four years prior to each two year follow-up interval and observed similar associations.
31 We used Cox proportional hazards modelling using time varying variables with the most updated information for PPI use and other covariates before each two year interval to calculate adjusted hazard ratios and 95% confidence intervals.
The strengths of our study include the large sample size and long duration of follow-up from two prospective cohort studies, with follow-up rates in excess of 90% in each two year cycle.
We used Cox proportional hazards modeling with an Anderson-Gill data structure for time varying covariates to adjust for other known or suspected risk factors prior to each two year interval to calculate adjusted hazard ratios and 95% confidence interval.
Similar(51)
The mineral fertilizers were applied yearly, while the fermented sheep manure at each two years in late winter.
Smaller peaks were observed in 2004 and 2006, each two years after severe dry spells.
From 0 to 30 working years, there is a decreasing trend in each five year phase.
Level four at key stage two represents a level that is expected of each eleven year old.
Hospitals with fewer than 25 patients diagnosed in each five year time period were excluded from the funnel plots.
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