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Standard approaches to genotype imputation will be applied in each study, followed by a similar approach to population stratification adjustment within each study using adjustment with principal components for genetic ancestry.
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A brief description of each study follows.
The following parameters were assessed: author, publication year, year of market introduction, type of prosthesis, number of primary cases, follow-up (in years) of patients in each study, follow-up (in years) after market introduction for each implant, number of revisions, and/or revision rate.
Each cohort study followed the rules for ethics and data protection set up in the country in which they were based.
The next section provides a brief overview of the specific reforms that were examined in each country case study, followed by a presentation of the key issues arising from the analysis of health financing functions and policy.
Informed consents were obtained from each participants and the study followed good clinical practices.
Thus, this cohort study followed up each child once to obtain medical record and home environmental information.
Written informed consent was also obtained from the head of each facility included in the study followed by verbal consent from the participating providers.
The study followed the participants for 6.5 years on average.
A University of Pennsylvania study followed 415 intravenous drug users over four years.
The study followed 56 teenagers aged between 14 and 19 for three months.
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