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Finally, the stress category of the fillet welding part of each specimen is evaluated based on a statistical approach of Albrecht's probability model.

In addition, the permeability of each specimen is evaluated using finite element (FE) simulation, which is then compared with experimental data.

Each specimen was evaluated to confirm histological diagnosis by an experienced consultant gastrointestinal pathologist (GIM).

Each specimen was evaluated for the presence of atherosclerotic plaque.

Each specimen was evaluated qualitatively, semiquantitatively, (score index from 0 to 3+), and quantitatively.

Each specimen was evaluated independently by two pathologists who were blinded to the patients' clinical features and outcomes.

Each specimen was evaluated in eight different tumour foci with 10 cells analysed in each area (total of 80 cells per specimen).

Each specimen was evaluated by the same pathologist to define the differentiation status of carcinoma tissues as well as the degree of dysplasia of adenoma tissues.

The quality of 90-bp long PE reads generated for each specimen was evaluated using FastQC software v0.10.1 (www.bioinformatics.babraham.ac.uk/projects/fastqc/, last accessed June 15 , 2015.

Next, NGF (or TrkA, p75NTR) expression in each specimen was evaluated by computing the ratio of NGF (or TrkA, p75NTR) band intensity in tumour to that in the corresponding normal epithelium (T/N ratio).

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