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While the small number of volunteers limits statistical comparisons between each solicited adverse event at each immunization time point, the frequency of each solicited adverse event appeared comparable in all groups.
The exact two-sided Cochrane-Armitage test for trend using rank scores was used to test for a dose effect for each solicited adverse event; for these analyses, the Recombivax group was assigned a dose of 0 µg of AMA1-C1.
The incidence of each solicited AE of any or Grade 3 severity was similar between groups.
The incidence of each solicited general AE is reported per subject considering both doses 1 and 2 (Table 3).
The authors found that the incidence of each solicited AE of any or Grade 3 severity was similar between groups.
The incidence and intensity of each solicited and unsolicited local and general symptom was calculated with exact 95% CI per age strata for each group.
Similar(43)
The overall percentages of subjects reporting an AE after vaccine administration (21 days after each vaccination for solicited AEs and 31 days after each vaccination for spontaneously reported unsolicited AEs) were tabulated with exact 95% confidence intervals (CIs), by type and intensity (any grade and grade 3) for each age category, priming status, and group.
The overall percentages of subjects reporting an AE after vaccine administration (21 days after each vaccination for solicited AEs and 31 days after each vaccination for spontaneously reported symptoms) were tabulated with exact 95% confidence intervals (CIs) by type of AE and intensity (any grade and grade 3).
Each activity how proposals are solicited, for example, and how grantees are supported must be tailored to the chosen strategy.
Each local and general solicited symptom was reported by no more than 3.0%% of subjects in either group.
They were then visited at home on each of the next 6 days after each dose to record any solicited or unsolicited local and systemic reactions.
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CEO of Professional Science Editing for Scientists @ prosciediting.com