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Each of these alterations has already been reported in advanced cardiac hypertrophy and heart failure.
Each of these alterations could be modeled to contribute to cancer formation.
Each of these alterations results in oxygen delivery limitation to the tissue cells despite the presence of normalized systemic hemodynamic variables.
Although these studies can provide lists of the genetic events that contribute to the expansion of malignant clones, they do not inform us regarding the chronology or relative importance of each of these alterations in the cancer process.
In particular, we focused on locational differences in combinations of these genetic and epigenetic alterations because a locational imbalance in each of these alterations has been indicated (Samowitz et al, 2000; Luchtenborg et al, 2005; Park et al, 2006).
6 However, each of these alterations confers a modest only relative risk (RR < 2); thus, at present this information is unreliable for the clinic for common complex disease as well as for gastric cancer.
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That is why I believe the purpose of identifying each one of these alterations has its importance independently of the other.
Each of these epigenetic alterations serves to regulate gene expression without altering the underlying DNA sequence.
However, the relative and overall contribution of each of these molecular alterations to clinical decision making remains unclear.
As discussed in the next section, aging individuals and especially individuals with AD exhibit increased incidence of each of these physiological alterations [ 68, 106].
None of these alterations managed to change the largely tedious pattern of the match, with Kilmarnock particularly disappointing in midfield.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com