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Table 1 compares basic information on each of the registries in the study that could have such an influence.
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Sepsis-related deaths from 2002 to 2010 were identified based on International Classification of Disease, 10th Revision (ICD-10) codes reported for each record of the registry.
For each of the other registries, we estimated the proportion of RCTs with adequate reporting of random sequence generation or allocation concealment to be less than 12% based on a pilot sample of 100 records.
The comparable number of procedures reported to each of the other registries is presented in Figure 1.
The expected number was calculated from accumulated person-years and age-, sex-, and calendar period-specific cancer incidence rates in each of the cancer registries.
Observed numbers of male neoplasms were compared to the expected number derived from the age, sex and calendar period-specific cancer incidence rates in each of the cancer registries.
18 The proposition becomes more implausible when one considers the gross error that pathologists and cancer registry staff would have to have been making, for thousands of patients each year, consistently over many years, and in each of the cancer registries across all four UK nations, to explain the longstanding survival deficit between the UK and other European countries.
To assess any possible excess of second primary neoplasms after NHL, we compared the observed number of neoplasms to the expected number derived from the age-, sex- and calendar period-specific cancer incidence rates of first primary cancers in each of the cancer registries.
Each of these registries was certified by the NAACCR for data completeness and timeliness at the gold or silver level for these years.
This will dilute the effectiveness of the registries.
None of the registries contain clinical data.
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