Sentence examples for each individual lymphocyte from inspiring English sources

The Bretscher-Cohn model solved many of the difficulties of the previous models of Burnet and colleagues [ 2, 3] and Lederberg [ 4], which proposed a window of obligatory tolerance induction in the ontogeny of the animal [ 2, 3] or of each individual lymphocyte [ 4].

In an attempt to see whether the observed differences in cytokine and immunoglobulin production between patients and controls or between PBL and TIL of patients could be due to differences in the composition of individual lymphocyte preparations, we performed an immunophenotypic analysis of each lymphocyte preparation.

Using the mouse model of Salmonella infection, IFNγ production has been demonstrated in a variety of individual lymphocyte subsets.

This difference in acute phase peak viral load provides a measurable indicator of protection in future adoptive transfer experiments, essentially establishing a 3 4 log10 reduction in viral load as the benchmark for success, irrespective of whether the transferred cells are bulk lymphocytes, individual lymphocyte subsets, combinations of lymphocyte subsets, or in vitro manipulated lymphocytes.

However, individual lymphocyte subsets were not checked, and a functional assay of lymphocytes was not conducted.

Of the 12,022 genes surveyed, 2,641 were differentially expressed between individual lymphocyte subsets.

Haplotype frequencies of individual lymphocyte subsets were also tested for some chimeric mice, but did not reveal significant differences from the respective frequencies of total lymphocytes (data not shown), suggesting that there is no specific haplotype bias for individual lymphocyte subsets in chimeric mice.

HeLa cells (NCAM- and CEA-negative) were used to demonstrate equivalent nonspecific killing by all three populations thereby confirming that the specific killing observed was because of CIR activity and not because of any altered killing properties of the individual lymphocyte populations.

Individual lymphocytes occur in the vicinity of these particles, but no appreciable inflammatory changes are visible, and no giant cell or granuloma formation can be observed".

Accordingly, the overall function of the immune system may be defined as maintenance of molecular (antigenic) homeostasis (Poletaev, Stepanyuk and Gershwin 2008) and thus a collective basis for reactivity – not the discriminatory power of individual lymphocytes – determines identity and immune specificity (Daëron 2014).

Therefore, computational models are ideal for directly testing the emergence of collective responses from signaling within individual lymphocytes.