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Despite the protection of each individual cellular compartment by its own set of ROS-scavenging enzymes, APX1-deficient Arabidopsis plants exhibited the oxidation of chloroplastic, mitochondrial and membrane-bound proteins, suggesting the key role of cytosolic APX1 enzyme in the cross-compartment protection of adjacent compartments (Davletova et al. 2005).
Also shown in Additional file 1: Figures S13 S21, the density for each individual cellular species shows the formation of distinct spatial structures according to interaction type.
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The contradictory prognostic value of HSP-90 overexpression between diffuse and intestinal type of gastric cancer patients could be attributed to the different signals produced from the tumor microenvironment and the individual cellular characteristics of each tumor histological type.
This is likely due to any given miRNA targeting multiple mRNAs, each of which has a different function in an individual cellular context [ 11- 13, 61].
Although the mean GFP intensity and the mean cell area appear to be correlated on each of the substrates, we examined whether this correlation extends to the individual cellular level.
This kind of modeling is already in use to study individual cellular processes like metabolism.
It now seems that the SCN acts as the "master clock", coordinating the activity of billions of individual cellular clocks across the body.
Single-cell analysis has become a powerful method to construct a new type of whole cell sensor integrating with individual cellular responses all together.
Individual cellular rings were hooked around two pins separated by 10 mm, and successfully cultured for 6 d without breakage.
However, because previous reports were made by measuring population-averaged overt rhythms of physiology, what is happening in individual cellular circadian clocks has remained obscure.
Our system can be modified to add and remove cellular components with ease, thereby enabling the study of individual cellular contributions in the tumor microenvironment.
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