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There are about 30 million nucleosomes in each human cell.
Yet all that information is compressed into each human cell.
Consider the fact that each human cell contains approximately 2 metres (6 feet) of DNA.
Both the consortium and Celera aim to sequence the human genome, which means determining the order of the three billion chemical units in the DNA, the genetic information possessed by each human cell.
Biochemist who shared the Nobel Prize for work that led to new treatments for cancer and cystic fibrosis Each human cell contains about 100,000 different proteins, which carry out jobs such as speeding up chemical reactions and acting as signals.
They identified as the likely source of the problem a region on Chromosome 7, the seventh of the 23 pairs of giant molecules in which each human cell's DNA is packaged.
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The human genome is minuscule in size -- two copies are packed into the nucleus of each ordinary human cell, itself too small to be seen by the naked eye -- but vast in its informational content.
About 70,000 lesions per day were estimated to happen in each normal human cell [10].
The estimated human nuclear DNA content of 100 μL is 872 ng, as each diploid human cell contains 6.6 pg of nuclear DNA as reported by Lo et al. [ 6].
The discovery, if confirmed, could open new insights into the higher order control of the genes, like the critical but still mysterious process by which each type of human cell is allowed to activate the genes it needs but cannot access the genes used by other types of cell.
Physically, the genome is minuscule -- two copies of it are packed into the nucleus of every ordinary human cell, each one of which is about a fifth the size of the smallest speck of dust the eye can see.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com