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Finally, 41 patients in each group were analyzed (Figure 2).
The chemical compositions of each group were analyzed by X-ray Fluorescence (XRF).
The statistical significance of each group were analyzed by the paired t test (*p < 0.05 and **p < 0.01).
To monitor for acute myelotoxicity, white blood cell (WBC) counts and platelet counts in the blood from the tail vein of 5 mice from each group were analyzed at 6 and 14 days after treatment.
Histology (n = 3 for each group) was analyzed at 2 and 5 weeks, and micro-computed tomography (μCT) and torsional biomechanics (n = 12 for each group) were analyzed at 5 weeks.
The event risks during the observation period for each group were analyzed using a Cox proportional hazard model, in which the independent valuables were taken from the results of a Chi-square test with significance level p < 0.1.
Seizures were analyzed using the Lamberty & Klitgaard score and kindling was considered as established after at least three consecutive seizures of score 4 or 5. Cumulative seizure scores for each group were analyzed using repeated measures of ANOVA followed by Tukey test.
Data from each group were analyzed separately.
Three to 4 animals from each group were analyzed.
For quantitative analysis, at least 6 nonadjacent sections for each group were analyzed.
Changes within each group were analyzed using the analysis of variance (ANOVA) for repeated measures.
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