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An approximately equal number of simulees received any one of the seven booklets within a group (with random assignment), and each group was administered all seven booklets.
RTX (25 ug/kg in 0.8 ml saline) or vehicle (n = 8 for each group) was administered directly into the gastric lumen with a thin needle attached to a glass syringe.
Single unit recordings were differentiated and compiled into rate histograms (1 second bin width) using wave-mark template in SPIKE 2. RTX or vehicle (n = 4 for each group) was administered into stomach as previously described.
Each group was administered drug for four consecutive days.
Each group was administered with pure valsartan, marketed formulation, liquid SMEF (F9), S-SMSD, and S-SMFD each at the dose of 5.0 mg/kg.
Each group was administered daily by intraperitoneal injection, AS-10 or scrambled ODN at a dose of 10 mg kg−1 or vehicle alone (sterile normal saline, pH 7.4).
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Eight rats in each group were administered for 12 weeks and weighed on weekly basis.
Eight mice for each group were administered with GST-pi siRNA atelocollagen complex or atelocollagen alone.
Mice (4 heads each sex, each group) were administered nasally the TNF/CHP nanoparticle preparation combined with the IVV once a week either once or four times for acute or repeated toxicity, respectively.
Mice (n = 3 in each group) were administered edaravone 0 or 3 hours following CCI or vehicle 3 hours following CCI, with the Et signal evaluated 4 hours after injury as a measure of O2∙− generation.
The animals in each group were administered, via oral gavage, 20 or 100 mg/kg KAI407, 2.5 mg/kg atovaquone (in 0.5% [wt/vol] methylcellulose and 0.5% [vol/vol] Tween 80 in distilled water), or vehicle only.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com