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Values reported correspond to median values for the population mutation rate above the diagonal, with the mutation-scaled immigration rate (M) for each direction of migration below the diagonal with source populations as rows and receiving population as columns.
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The aim of the audit was to quantify the number of markers migrating, distance and direction of migration and conditions under which markers migrate.
Duning et al. demonstrated that the knockdown of KIBRA in cultured podocytes increased the migrating speed, but caused a frequent change in the direction of migration, resulting in inefficient directional migration.
In addition, neutrophils isolated from the Cdc42GAP knockout mice had an increased ability to migrate, but the direction of migration was disrupted [ 41].
We conclude KIF11 is a key downstream molecule that responds to directional cues in chemotaxis to govern the direction of migration.
The leading process of a migrating interneuron is oriented towards the direction of migration and thus provides an index of orientation of migration [24] [26].
By having two antennas placed close to each other we were able to determine both timing and direction of migration of individual fish.
7) The authors describe that 50% of posterior filopodia do not contain actin (in the subsection headed "Migrating PGCs extend specialized filopodia in the direction of migration").
10.7554/eLife.05279.043 Author response image 2. DOI: http://dx.doi.org/10.7554/eLife.05279.043 7) The authors describe that 50% of posterior filopodia do not contain actin (in the subsection headed "Migrating PGCs extend specialized filopodia in the direction of migration").
In short, people in the most affluent tertiles of social or material deprivation cannot migrate to a more affluent tertile; the only direction of migration permissible (as the data are categorised) are within tertile, or downwards.
As growth cones migrate, they extend dynamic lamellipodial and filopodial protrusions in the direction of migration.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com