Specific medical record data gathered for each patient included age, gender, uveitis anatomic classification based as defined by Standardization of Uveitis Nomenclature criteria [11], laterality, Snellen visual acuity, associated systemic diagnoses, and the presence of other local disease processes potentially contributing to the SRD (e.g., concomitant choroidal neovascular membrane).
Pregnancy e. Concomitant food intake and new formulations f.
However, we did demonstrate that the greatest bias between PHTfree and PHTadj_free was seen in hospital inpatients, possibly due to other factors (e.g., concomitant drugs, organ failure) that can impact PHT pharmacokinetics.
This argument hinges on the idea that adaptation to one environment reduces fitness in others, resulting in genetic trade-offs between environments (genotype × environment interactions, G × E) and concomitant patterns of local adaptation (Kawecki and Ebert 2004).
These data may reflect the predominantly inpatient population studied, where shifts in phenytoin dosing and also changes in other factors (e.g., concomitant) were needed for patients with unstable clinical status.
If MAP fell below 50mmHgg (40 mmHg for neonates) or more than 20% below the target MAP, or if HR exceeded the age-adjusted maximum with no other explainable cause (e.g., concomitant medication, surgical stimulation or hemorrhage/hypovolemia), open-label fenoldopam administration was discontinued until MAP and HR returned to protocol limits.
Thus, in addition to megalin decrease, RenTg mice showed decreased expression of E-cadherin concomitant to the appearance of tubulointerstitial fibrosis and increased expression of FSP-1; AT1 receptor antagonism reversed to normal these phenomena.
Analysis of fixed samples of cultures exposed to Act/Chi, shows that the onset of differentiation into mesendoderm is associated with a decrease in the levels of E-cadherin concomitant with the onset of Bra expression (Additional file 2: Figure S2A).
Whereas Wnt-3a only slightly induced EMT in NCI-H226, AEG-1 depletion notably elicited a change in NCI-H226 cells from the mesenchymal phenotype to an epithelial phenotype as manifested by increased expression of the epithelial marker E-cadherin concomitant with a downregulation of the mesenchymal marker Vimentin.
An alternative explanation is less likely (e.g. concomitant medications, concomitant diseases).
An alternative explanation (e.g. concomitant medications, concomitant diseases) is inconclusive.
