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A novel finding in rodents was the discovery of a site of edema formation (arrowhead in Fig. 3 E), a pathological alteration that does not endure the tissue processing required for in vitro methods, and is thus not visible in traditional histology.
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The predictive performance of a candidate gene set, that is, its capacity of discriminating a given target class (e.g., a pathological state), can be measured inducing a classification model on that set and using some test instances to evaluate this model in terms of metrics such as accuracy or ROC area [ 18].
– Symptomatic; the drug relieves symptoms arising from a pathological condition (e.g. analgesics).
Our hypothesis is that LPI is an endogenous factor secreted upon a pathological event (e.g. after ischaemia, wound healing or from cancer cells) (Pineiro et al., 2011; Pineiro and Falasca, 2012), leading to increased angiogenesis.
The presence of apo A-I and apo E in pathological deposits, such as atherosclerotic lesions and neurotoxic Alzheimer's plaques, suggests a possible contribution of SR-A-dependent adhesion of macrophages to an inflammatory microenvironment.
The hypothesis of a pathological role for apo E proposed above is in contradiction with the atheroprotective role of plasma apo E established in hypercholesterolemic apo E−/− mice (81).
This is necessary in order to avoid problems caused by the fact that W is a continuum variable (e.g., pathological cases where some property does not hold on measure-zero subsets of (mathcal {W})), We call a helper data scheme Zero Leakage if and only if forall_{{mathcal{V}}subseteq {mathcal{W}}}quad {mathbb{P}}[S=s|Win{mathcal{V}}]= {mathbb{P}}[S=s].
No cases with C9ORF72 expansion showed excessive tau and Aβ pathology (i.e. commensurate with a pathological diagnosis of AD) for age.
In some cases, however, tachycardia occurs without apparent cause or as a complication of a myocardial infarction (heart attack) or heart disease and is an arrhythmia i.e., a pathological deviation from the normal heartbeat rhythm.
This indicates that both factors converge in a similar range, i.e., a pathological range.
Pathological findings revealed no tumor cells in either the resected specimen or the lymph nodes (i.e., a pathological complete response).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com