Functional impairments from central nervous system (CNS) dysfunction experienced by pediatric patients with cancer diagnoses are well documented.
There is mounting evidence that conventional screening tests are insufficient to capture the degree of cognitive dysfunction experienced by ICU survivors.
The initial SOFA score can be used to predict the degree of organ dysfunction or failure present at admission, delta SOFA score during hospital stay, and total maximum SOFA score represents the cumulative organ dysfunction experienced by the patients [ 20- 22].
It is hoped that this will in turn facilitate the development of theoretically grounded cognitive interventions aimed at tackling the symptoms of poor concentration and worry which contribute to the distress and dysfunction experienced by anxious individuals.
1 2 Our group has previously defined WTC-LI as the chronic inflammatory lung dysfunction experienced by a subcohort of firefighters with intense exposure to WTC dust. 1 2 It is characterised by primarily obstructive respiratory dysfunction with substantial and persistent losses in forced expiratory volume in 1 s (FEV1)% predicted to ≤77% in the subsequent 6.5 years postexposure.
This was accompanied by a reduction in their proliferation, and that of neural progenitors in the subventricular zone and dentate gyrus, and it was suggested that this may represent a cellular substrate of cognitive dysfunction experienced by breast cancer patients receiving TAM therapy.
However, the gluco-regulatory dysfunction experienced by mice treated with rapamycin while on a high fat diet highlights a potential concern with regard to the therapeutic use of rapamycin in humans, in which the dietary intake is much more varied in both content and composition.
The findings from this study are consistent with the hypothesis that cardiac autonomic dysfunction is experienced by individuals with depression, especially decreased parasympathetic nerve activity (as evidenced by decreased values of the time domain indexes).
Persistent erectile dysfunction would be experienced by the majority of patients who have RRPC before undertaking cryotherapy or beginning ADT, as a result of prior treatment, 6 which is accounted for in the baseline utility level for all cohorts (as detailed in online supplementary material).
It consists of 24 yes/no items, which represent common dysfunctions in daily activities experienced by patients with low back pain.
