Sentence examples for dysfunctional expression from inspiring English sources

For instance, miR-122a-deficient mice developed hepatosteatosis as a consequence of dysfunctional expression of genes involved in TG synthesis, storage and secretion12,13.

Dysfunctional expression of CRC subunits has been associated with leukemia.

Authors suggested that impaired decidualization and dysfunctional expression of genes related to Müllerian embryogenesis (like the downstream targets of HOXA10) could be critical to the development of endometriosis.

In this study, we observed that decreased (and dysfunctional) expression of Rorα (1 and 4) led to increased Akt2 mRNA expression and improved insulin sensitivity, and increased levels of basal and insulin-stimulated phosphorylation of AKT and of glucose uptake.

Since tapetum cells are either absent or dysfunctional in the mutants, we expected that the expression of tapetum-related genes would reduce significantly.

We suggest the data are consistent with decreased (and dysfunctional) RORα expression leading to derepression and increase of Akt2 mRNA expression.

Given the potential implication of dysfunctional CEACAM6 expression in the pathogenesis of IBD, we aimed to analyze the role of CEACAM6 SNPs in IBD susceptibility.

Dysfunctional CD127 expression [7], [22] suggests that failure of the IL-7/IL-7 receptor system may contribute to the loss of memory T-cell maintenance in HIV infection.

Dysfunctional perforin expression has been described at HIV seroconversion [63], however, the impact of early and prolonged treatment on this marker remains unknown.

Therefore, FNS might be conceived of as such a dysfunctional bodily expression of dysfunctional emotion processing.

However, in diseased tissues where the regulatory mechanism is dysfunctional, the expression of the gene module will be unordered or random.