Exact(16)
In some cases unitary pseudogenes are the direct remains of a gene that has become dysfunctional due to mutations.
These "conformational changes" can render the protein to become dysfunctional due to loss of native form or thermodynamically favorable if it allows either charged or hydrophobic regions of proteins to interact with either hydrophobic or charged NPs [25, 47, 48].
The creek and floodplain ecosystem had become dysfunctional due to the effects of altered storm water delivery following urban watershed development where the impervious surface reached nearly 30% in some sub-watersheds.
Increased mitochondrial biogenesis and increased mitochondrial density alone may reduce ROS production while at rest by providing new mitochondria to supplement those that are aged or dysfunctional due to oxidative stress, as well as increasing mitochondrial membrane surface area to facilitate diffusion and dissipation of proton gradients, thereby reducing the slowing of electron flow in the ETC.
Over 1,400 executions later with almost 3,000 mostly men lingering for years on the nation's death rows, capital punishment looks increasingly dysfunctional due to the continued judicial failure to satisfactorily regulate the way death sentences are reached.
As strongly inferred in the downgrade of U.S. government debt by ratings agency Standard & Poor's, the democratic political system in the United States, and by extension in the U.K. and Eurozone, has been rendered dysfunctional due to general ineptitude, economic ignorance and ruinous internecine political conflict.
Similar(44)
6) The knockout of essential genes from the autophagic cascade entails a major cellular dysfunction due to accumulating, dysfunctional mitochondria (and perhaps other organelles and protein aggregates).
The proteins that are expressed in cancerous cells, in all likelihood, possess the following interrelated/interdependent defective features: a. Dysfunctional properties due to lack of structural/architectural properties and impaired integrity; b.
Participants: 7 patients with dysfunctional spasticity due to acquired brain injury underwent serial soleus H-reflex recordings before and 4 hours after the ITB delivery mode was changed from simple- to complex-continuous.
These results suggest that rapa also suppresses cell death initiated by dysfunctional telomeres due to inactivation of the essential telomerase subunit Est1p.
Myocardial viability refers to dysfunctional myocardium due to ischaemia, but with the potential to recover its function.
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