Sentence examples for dysfunctional copy from inspiring English sources

The fact that the hairlessness of the heterozygous pigs is intermediate indicates, that one functional copy of the gene in question is not enough to maintain a normal skin phenotype (or one dysfunctional copy can impair the "normal" pathway).

At the genetic level, a mutated gene can be dominant or recessive depending on how many dysfunctional copies are required to exert its effect (Table  2).

The tandem duplication of X-R55 was quite similar to the ZNF91 subfamily of primate-specific zinc finger genes, consisting of large gene clusters with some dysfunctional copies [ 34].

This leads to a possible explanation for why sex is useful: having two sets of genes – one from each parent – allows for the possibility of inheriting new, beneficial forms of a gene, while protecting the offspring from dysfunctional genes, because if one copy of a gene is damaged, the other copy can kick in and mask the damaging effect.

Put differently, her somewhat dysfunctional family has provided far livelier copy.

In this study, c- myc and CCND1 may be dysfunctional due to the observed increased copy number, and it is possible that protein expression is increased as a consequence which may be a route to muscle-invasion.

Additional mechanisms, including but not limited to a template copy mechanism initiated by short dysfunctional telomeres, might be responsible for generating new telomere DNA.

Replacing the dysfunctional or deficient gene with a functional copy has been achieved by administering the functional protein (Escobar 2013) and more recently by using gene therapy (Gaudet et al. 2013).

Cases with PTEN FISH homozygous loss included all those where both copies of the PTEN gene were deleted or one copy was deleted and the second copy dysfunctional because of associated ETS gene rearrangements.

The bookstore gave the president a copy of "Freedom," a new novel by Jonathan Franzen about a dysfunctional family in America.

Based on differences for DNA copy numbers and transcript amounts, we hypothesized that the basis of MSC3 phenotype may be dysfunctional mitochondrial complex I and/or complex V due to lower amounts of the NAD5 and ATP4 proteins, respectively.