Sentence examples for dysfunctional based on from inspiring English sources

We selected four candidate variations to be likely dysfunctional based on three criteria: (i) nonsynonymous coding variations that cause a missense or nonsense change, (ii) variations located in the polymerase core domain (amino acid residues 1 to 445), and (iii) missense variations predicted to be deleterious or damaging on protein function by SIFT and Polyphen.

The second SVM predicts whether an ATM/p53 dysfunctional sample is either ATM- or p53-dysfunctional based on the FIs of the cluster I-IV genes.

The assumption that pseudogenes are dysfunctional is based on the fact that pseudogenes do not code for proteins.

The first SVM predicts whether a sample is either ATM/p53 functional (F) or ATM/p53 dysfunctional (D) based on the FIs of the cluster I genes.

The source of the discomfort experienced in each subtype of burnout seems to come from very different coping strategies and dysfunctional attitudes based on the level of dedication at work [ 24].

Here is a docu-Jacobean nightmare, and a dysfunctional stepfamily drama, based on the career of Australia's most notorious serial killer.

Upham joined the star-studded cast of John Wells' dysfunctional family drama based on the Pulitzer-winning play by Tracy Letts.

The designers of the comprehensive system understood that this rigid, lifelong stratification would be dysfunctional in an economy based on information.

"The 2nd April High Level Meeting is intended as a landmark step towards adoption of a new global sustainability-based economic paradigm for human happiness and well-being of all life forms to replace the current dysfunctional system that is based on the unsustainable premise of limitless growth on a finite planet," the Bhutan government Web site asserts.

We examined the effectiveness of a novel behavior modification method for dysfunctional and impulsive habits, based on non-removable reminders (NrR).

Its downregulation is in line with the hypothesis of dysconnectivity based on dysfunctional oligodendrocyte-neuronal interactions in schizophrenia [ 65, 67].