Many of these "false-positive" patients had organ dysfunction variables just below threshold for classifying as organ dysfunction.
However, besides lactic acidosis and oliguria, range limits for organ dysfunction variables are missing in the 1992 publication [ 2].
This may be because more organ dysfunction variables are used in the APACHE II and PIRO scores.
In Table 1, the diagnostic criteria for sepsis and organ dysfunction variables in the 1992 and 2003 definitions are specified and compared.
In Table 1 the diagnostic criteria for sepsis and organ dysfunction variables following the 2003 definitions and those used in the present study are specified.
With respect to the 2003 sepsis definitions, organ dysfunctions were defined according to the limitations for organ dysfunction variables and tissue perfusion variables (hyperlactatemia) as presented in Table 1.
Organ dysfunctions were defined according to the limitations for organ dysfunction variables and tissue perfusion variables (hyperlactatemia) as given in the original publication [ 3] and presented in Table 1.
However, detailed accounts of ventilator settings, physiologic variables and organ dysfunction variables on the group level have appeared elsewhere [ 8].> -wrap-foot> Varees are for all animals in the experiment (n = 30) from 0 to 5 hours.
The APACHE II score contains organ dysfunction variables, such as mean artery pressure, creatinine, and oxygenation, but other variables did not reflect organ function, so its predictive value was weaker compared with the PIRO score.
In the literature, a long period of ischemia and longer duration of resuscitation efforts are associated with poor outcome [ 27, 28], and the timing of the ischemic insult and the length of the reperfusion have been shown to correlate with endothelial dysfunction variables and biochemical or histological evidence for cellular damage [ 25, 29].
