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Increased BNP levels have been described in septic patients, which is caused by several factors; for example, inflammation, myocardial dysfunction, severity of global tissue hypoxia, fluid management, vasoactive drugs and renal dysfunction [ 7, 20].
For subjects exclusively fed by mouth, a dose-response relationship was observed between feeding dysfunction severity and poor nutritional status.
Organ dysfunction severity was defined according to SOFA.
The new organ dysfunction severity was similar in both groups (P = 0.37).
The implementation of the developed protocol reduced the degree of organ dysfunction severity and was associated with significant survival benefit.
Also, S100B was associated with brain dysfunction severity as higher levels were observed in fatal comatose than other patients.
Similar(42)
Therefore, current trial designs allow the enrollment of a heterogeneous population of patients with varying numbers of organ dysfunctions, severity of illness scores, and predicted risk for death [ 5].
Several studies link hematological dysfunction to severity of sepsis.
Historically, critical care outcomes have been predominantly attributed to the patient's genetic predisposition, baseline dysfunction, and severity of insult.
Increased concentrations of adhesion molecules have also been associated with multiple organ dysfunction, disease severity, or death [ 23].
Increased concentrations of CAMs have also been associated with multiple organ dysfunction, disease severity, or death [ 11].
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