Sentence examples for dysfunction processes from inspiring English sources

Thus, the double hit theory, mutations both in mitochondrial DNA and modifying genes aggravating the symptom, throws new light on mitochondrial dysfunction processes.

Ultimately, excitotoxicity is a result of synaptic dysfunction processes, which involves the excessive glutamate receptor activation and neuronal degeneration [ 38].

However, the duration of exposure to the study drugs may not have been long enough to reverse the effects of years of diastolic dysfunction processes in patients.

Whether it is screening for metabolic disorders at birth, hearing deficiency, and eye infections, orthopaedic dysfunction processes to routinely screen for such problems has become part of the standard of care to avoid, prevent, or mitigate significant illness, disability, or even death later on.

Further studies are necessary to introduce new therapeutics to control the endothelial dysfunction process and improve the prognosis.

Knowledge of the likely factors leading to the clinical problem or dysfunction, the processes involved, and how these processes emerge or operate, can contribute to the treatment development research [ 18].

This suggests that mitochondrial dysfunction affects processes in the daf-2/insulin receptor pathway and in parallel to the TGFβ pathway.

Healing has a much poorer prognosis in cases of suspected tubal dysfunction, adhesive processes, tympanic fibrosis, bilateral disease, and defects of the entire tympanic membrane [ 10– 10].

In tumors, changes in gene dosage due to low level copy number alterations may also lead to small alterations in expression of multiple genes, which together could contribute to dysfunction of processes manipulating the genome, resulting in more error prone cell division cycles.

In this respect, Hayden and Tyagi [ 8] point out that SUA values from the upper third of the physiologically normal range (> 4.0 mg/dL) have a harmful impact on the vascular endothelium leading to endothelial dysfunction through processes of oxidative stress.

Organ failure in sepsis is provoked by cellular dysfunction, a process related to pro-oxidative conditions and dysfunctional mitochondria.