Sentence examples for dysfunction or deficiency from inspiring English sources

Some have hypothesized that melanocyte dysfunction or deficiency underlies the loss of skin pigmentation observed in vitiligo.

Cystic fibrosis is caused by dysfunction or deficiency of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, an epithelial chloride channel that has a key role in maintaining homoeostasis of the airway surface liquid layer in the lungs.

Factor VIII (FVIII) is an important protein in the blood coagulation cascade and dysfunction or deficiency of FVIII causes haemophilia A. Replacement therapy with exogenous recombinant FVIII (rFVIII) works as a substitute for the missing or non-functioning FVIII.

Table 1 lists each human serpin, together with brief notes in regards to each molecules function and the consequence (where known) of dysfunction or deficiency.

Chronic BBB breakdown is associated with dysfunction or deficiency in pericytes, which has been shown to cause CNS degeneration as previously discussed.

This group of inherited metabolic disorders is characterized by accumulation of different sphingolipids due to dysfunction or deficiency of the corresponding lysosomal enzymes.

Other causes of hair loss such as diffuse effluvium due to iron deficiency, infection, thyroid dysfunction, or chronic deficient diet should be excluded.

The National Comprehensive Cancer Network (NCCN) guidelines recommend treatment for pain, emotional distress, and anemia as well as optimizing treatment for sleep dysfunction, nutritional deficiency or imbalance, and comorbidities [ 9].

The LSDs are a group of rare inherited metabolic disorders, which result from lysosomal dysfunction that stems from mutations or deficiency of a single lysosomal enzyme.

According to the guidelines, 3 active vitamin D is recommended for osteoporotic patients who are elderly, have renal dysfunction, or have 1α-hydroxylase deficiency.

The most common cystic fibrosis (CF) manifestation is the progressive chronic obstructive pulmonary disease caused by deficiency, dysfunction, or absence of the CFTR (Cystic Fibrosis Transmembrane Regulator) protein on the apical surface of the cells in the respiratory tract.