Since 1,5-AG levels can be altered in chronic renal and liver diseases, we excluded two patients because of hepatic dysfunction; none of the participants had stage 3 or higher chronic kidney disease.
However, results from the baseline SHIP examinations, for which these measurements were available, indicate that most of the participants with thyroid dysfunction have the subclinical form [ 39].
Moderate physical activity was performed at least once a week by 63% of the participants; fatigue-related dysfunction was reported by 59% and back pain by 45% (Table 1).
Some of the participants explained their sexual dysfunction because of vaginal dryness.
Baseline characteristics of the participants including severity of sexual dysfunction were comparable across the two groups (Table 2).
None of the participants had heart failure, renal dysfunction or coronary artery disease at the baseline visit.
In the informed group, 44percentt of the participants reported that they experienced erectile dysfunction; in the uninformed group, that figure was only 15percentt.
Furthermore, we measured MVF, in the homes of the participants, whereas forearm plethysmographic methods applicable in clinical settings might be more sensitive for detection of vasomotor dysfunction [ 28].
Ethical concerns emerge in the research setting, pertaining to the detection of cognitive dysfunction in participants, validity of consent, disclosure of abnormal results if screening is pursued, and recommended level of intervention by investigators.
