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Corneal endothelial dysfunction is a substantial problem in FECD, and it is accompanied by visual disturbance which provides a major indication for corneal transplantation surgery [138].
Similar(59)
Neurological dysfunction is a prominent feature of most peroxisomal disorders30.
Substantial clinical and experimental evidence suggests that endothelial dysfunction is an early marker for the initiation and progression of atherosclerosis [ 27].
Lebanon's dysfunction is an extreme case.
Even if there are not yet any prospectively controlled studies on the effects of revascularisation, there is a substantial amount of clinical evidence that patients with reversible LV dysfunction may benefit from a revascularisation procedure [75, 76].
There is a substantial body of published research which points to an association between hyperglycaemia and organ/tissue dysfunction.
This is a substantial upgrade".
That is a substantial amount.
This is a substantial grievance.
"It is a substantial industry.
"It is a substantial change.
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