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Myocardial dysfunction is a fundamental aspect of sepsis, but goal-directed therapy and accurate diagnosis at the bedside is a difficult challenge.
High uric acid levels could potentially increase the risk of cardiovascular disease via several biological mechanisms; however, recent studies have suggested that endothelial dysfunction is a fundamental mechanism whereby uric acid may affect cardiovascular function.
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Neurological dysfunction is a prominent feature of most peroxisomal disorders30.
Lebanon's dysfunction is an extreme case.
Results from our sleep paradigm can also be viewed as the endpoint behavioral representation of synaptic connectivity and dysfunction of circuits in general, which is a fundamental theme in neurodevelopmental syndromes including RTT (Shepherd and Katz, 2011).
The diaphragm is a fundamental respiratory muscle whose dysfunction may be very common in patients undergoing mechanical ventilation.
Endothelial dysfunction that is associated with oxidative stress and inflammation is a fundamental feature of CVD.
Regulation of hypothalamic pituitary adrenocortical (HPA) axis activity by stress is a fundamental survival mechanism and HPA-dysfunction is implicated in psychiatric disorders.
"That is a fundamental difference.
This is a fundamental change".
That is a fundamental fact.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com