The high spatial and temporal resolution of the system has allowed us to visualize the living hematopoietic tissue with exceptional clarity and track the architecture and dynamics of cell division, cell migration and cell death.
The dynamics of nuclear division was quantified by confocal microscopy and image processing.
(2013) quantitatively extracted the dynamics of nuclear division by using differential interference contrast microscopy and image processing.
To quantitatively analyse the dynamics of cell division, 120 cytokinetic events were randomly selected from movies at 2, 4 and 6 DIV.
Our model for the first time integrates real data on age-dependent dynamics of HSC division rates, pool size, and accumulation of genetic changes and demonstrates that somatic evolution is not rate-limited by the occurrence of mutations, but instead results from aged microenvironment-driven alterations in the selective/fitness value of previously accumulated genetic changes.
To verify this concept in a situation where the ground-truth was known, we analyzed ribbon evolution in an established computational model of the colonic crypt (van Leeuwen et al., 2009; see the Supplemental Experimental Procedures) and verified that the changes in the ribbon width along the crypt axis reflected the temporal dynamics of cell division at the crypt base.
Implications and future directions This work exemplifies the novelty of observing the dynamics of cell divisions in a live vertebrate organism.
Characterization of the PG dynamics in chloroplast division is important for an understanding of how the chloroplast division machinery has been modified from the original cyanobacterial division machinery by the eukaryotic host cell and how the ancestral algae regulated chloroplast division during the early stages of evolution.
The product of one empire on the wane, he failed to understand the new empire's mentality, never grasping the dynamics of Congress and the division of powers.
By introducing function in a population dynamics approach, I study the role of division of labor in tissue optimality when cell turn-over and limitation of space and resources are imposed as natural restrictions of a living tissue.
For divisions, the case is more complex: the cell often undergoes a stereotypical pattern of division in which the dynamics of each daughter cell are dependent.
