Because replication pause events exist at many sites during mt-replication, so too could the dynamic competition, double strand melting, and subsequent mispairing occur at multiple locations.
Whereas perfect (or nearly perfect) tandem repeats vary by copy number and are dynamic because of strand slippage during DNA replication, highly divergent repeats are relatively stable structural genomic elements, but their functional role has so far been insufficiently studied.
The present study demonstrates that the longitudinal dynamic behaviour of the strands is governed by coupled extensional-torsional oscillations.
Our structure reveals a monomeric form of Mdm12 with a conformationally dynamic N-terminal β-strand; it differs from a previously reported homodimeric structure where the N-terminal β strands where swapped to promote dimerization.
During this pause event, dynamic competition between the N-strand and the D-strand can lead to the melting of the N-strand from the T-strand.
Specifically, after the melting of the N-strand due to dynamic competition, the 3′ end sequences of the N- strand inaccurately rebind (mispair) to complementary sequences of the T-strand.
The central dynamic of "Stieglitz, Steichen, Strand" is just as complicated.
The latter was acquired during dynamic tests on a stranded steel cable, undergoing both sinusoidal and random flexural vibrations.
In a new study, researchers reveal a wholly unique DNA methylation pattern in D. melanogaster, finding DNA methylation to be very localized, strand asymmetrical, dynamic, concentrated in CA- and CT-rich five base pair motifs, and most likely involved in gene expression (Takayama et al. 2014).
The WPT gave a dynamic focus to many other strands in alternative theatre.
