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Social engagement provides dynamic stimulation for older individuals that influences cognition.
Lee and Bader40, for example, found that static and low-frequency dynamic stimulation inhibited chondrocyte biosynthesis, while physiological frequencies of 1 Hz had stimulatory effects – a finding which was later confirmed by multiple independent research groups utilising dynamic stimulation in various culture systems41,42,43,44.
It is now generally accepted that short intermittent loading (1 5 hours/day) enhances chondrogenesis6,39, while continuous dynamic stimulation is likely to have no significant45, or only adverse effects on chondrogenesis46 in most culture systems.
The conversion from performance demands to basic design data is done by means of analytical methods, finite element calculations, and dynamic stimulation.
Dynamic stimulation of PP, PF, PA and PEG constructs resulted in a respective increase in the GAGs by 33%, 53.4%, 240.5%, and 284.5%, compared to their static controls.
The vessel walls engineered under the dynamic stimulation for 8 weeks showed a dense and well-organized structure similar to that of native vessels.
Similar(25)
Use of an electric toothbrush to apply a vibrotactile stimulus may produce the desired attributes of not only dynamic mechanical stimulation, but also thermal and punctuate mechanical stimulation, with temporal summation.
Microfluidic artificial "vessels" for dynamic mechanical stimulation of mesenchymal stem cells.
Moving from static to dynamic laser stimulation requires a more complex electrical setup.
Dynamic laser stimulation (DLS) techniques have been introduced over the past few years to tackle the localization of dynamic failures.
To explore this hypothesis, a novel bioreactor was developed to study the effect of dynamic flexural stimulation on TEHV biomaterials.
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