In this study, Nigella sativa L. oil was extracted using supercritical carbon dioxide with full factorial design to determine the best extraction condition (pressure, temperature and dynamic extraction time) for obtaining an extract with high yield, antioxidant activity and thymoquinone (TQ) quantity.
In this way, a series of extraction experiments are designed to investigate the effect of different operating conditions such as extraction pressure (85 120 bar), extraction temperature (38 50 °C), CO2 flow rate (0.059 0.354 g/min), mean particle size (0.177 2 mm) and dynamic extraction time (20 120 min) on efficiency of the extracted essential oils.
Static and dynamic extraction modes were compared.
That new game is W.E.L.D.E.R. ($2 on Apple), which is short for Word Examination Laboratory for Dynamic Extraction and Reassessment.
The variables of interest in SFE were pressure, temperature, modifier volume, and dynamic extraction time.
A new method for the extraction of medicinal herbs termed ultrasonic-assisted dynamic extraction (UADE) was designed and evaluated.
High throughput, with six samples running simultaneously in a highly automated system working in dynamic extraction mode, has been achieved.
The importance of evaluated parameters could be arranged in the following order: temperature > pressure > dynamic extraction time.
The factors selected were extraction temperature, pressure, static extraction time, dynamic extraction time and carbon dioxide flow rate.
Final selected conditions for PSE were extraction temperature, 50 °C; static extraction time, 0 min; and dynamic extraction time, 30 min.
Separations can now be performed routinely in minutes using the new high 'g' dynamic extraction technology as opposed to hours with previous low 'g' technology.
