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Although control group participants were not calorie restricted, their diet during the study provided a healthy 30% of calories from fat with the recommended daily allowance of nutrients.
Inhaled corticosteroid use was permitted during the study provided that the steroid dose was stabilized for at least 6 weeks prior to the screening visit and throughout the study period.
Doubling of serum creatinine was considered to have occurred at the time when a serum creatinine value was found to be twice as high as the first measurement during the study provided that all subsequent values during follow-up remained at least twice as high as at baseline.
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BM provided clinical expertise to the team and participated in the design of the study, provided feedback during instrument development, and participated in drafting of the manuscript.
The ancillary analysis that controlled for weight change during the study provides additional insight into the possible effects of elevated depression symptoms and ADM use on CVD risk factor status.
Given the reduced susceptibility of C. glabrata to azole drugs (30 ), our observations that C. glabrata candidemia occurs more often in patients without hematologic malignancy and that these infections increased during the study provide useful data.
The decreasing concentration of available nectar during the length of the study provides a plausible explanation why high-strain bees collected nectar of higher concentration than low-strain bees; high-strain bees initiated foraging earlier in life when the more concentrated nectar was available.
For the case-crossover sub-study, we included only HIV-positive female adolescents who were HAART-naïve at enrollment but initiated HAART during the course of the study, providing adequate follow-up periods before and after the introduction of HAART (referred to as before HAART initiation and after HAART initiation).
The data obtained during this study provided evidence of a large conductive region beneath the surface of the Jigokudani valley that is underlain by a resistive layer at depths below 500 m.
Application of the different final potentials during the electrochemical study provides a close look to the oxidation kinetics.
As a result, some patients who were RCT pegloticase non-responders continued receiving pegloticase during the OLE study, providing additional information with regard to these relationships.
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