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Pulse oximetry, non-invasive blood pressure, and electrocardiography were continuously monitored during the induction period and at all times during the study procedure.
SL had been involved in acquisition of funding, manuscript revision and provided ideas during the study procedure.
None of the patients showed signs or symptoms of local anesthetic systemic toxicity during the study procedure.
If a participant withdraws the informed consent for participation during the study procedure the data will be deleted forthwith.
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Vasoactive drug infusion rates and ventilation settings were kept constant during the study procedures.
All aspects of animal care prior to, during and following the study procedures outlined below were overseen by the veterinary team of the Australian National Baboon Colony.
The pilot phase was conducted in 3 general practices over a 4-month period; during this time the study procedures were refined and projected recruitment rates confirmed.
In total, 147 patients underwent the study procedures during the designated period.
These processes will be monitored during the intervention by reflecting on the study procedures and participants' experiences.
The randomisation of scale order was considered as a gold standard to take into account any learning effect or, on the contrary, any fatigability during a study procedure incorporating several pain tools [ 26].
Because the Erasmus MC is a university hospital, during the study period the procedures were performed by six different orthopaedic surgeons with different medical assistants.
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