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Exact(16)
All structural constraints presented in the molecular connectivity diagram are used during the structure generation.
The only discordant response during the structure's dedication in 1923 was whether, with a capacity for 1,800 students, it was too large.
No additional solvents were required during the structure preparation process.
While they were doing that, they spotted a potential leak during the "Structure in Android App Design" session.
The fiber temperature increased from 120 °C to 160 220 °C during the structure development process.
The drift direction of upwellings becomes eastward during the structure phase (e.g., see Figure 6), when the F-region dynamo prevails.
Similar(44)
Five thousand hits were identified, and docking was performed to compare them with the hits found during the structure-based search.
It was surprising at times, people we thought were star candidates did not necessarily rise to the top during the structured process while others that we had dismissed as average candidates surprised us.
Molecular dynamics (MD) simulation, as a powerful tool for studying the kinetic process of inhibitors, can be used for identifying crucial factors that influence the association and dissociation processes of inhibitors during the structure-based drug design.
The capacity of our VS workflow to distinguish between hIKK-2 inhibitors and molecules that do no inhibit hIKK-2 was evaluated by applying it to a set consisting of 62 known hIKK-2 inhibitors (different from the 36 used during the structure-based pharmacophore generation; see Table S2) and 10,036 kinase decoys obtained from the Directory of Useful Decoys (DUD; http://dud.docking.org) [46].
All bond lengths and valence angles are fixed during the structure-solution process, as are all torsion angles around double bonds and those within rings.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com