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HR was similar at rest but during the second h of exercise was maintained at ∼14 beats/min higher in the dehydration trial compared with the control trial (P < 0.05).
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In our study, insulin sensitivity inversely correlated with temporal myo-inositol/Cr and myo-inositol/H2O ratios assessed during the second H-MRS.
Insulin sensitivity correlated positively with frontal NAA/Cr and NAA/H2O and temporal Glx/H2O and negatively with temporal myo-inositol/Cr and myo-inositol/H2O assessed during the second H-MRS (all P < 0.05).
In consequence of these changes, frontal NAA/Cr and NAA/H2O ratios assessed during the second H-MRS were higher in the high-IS group in comparison with the low-IS group (P = 0.0004 and P = 0.01, respectively).
Frontal and temporal Glx/Cr and Glx/H2O ratios assessed during the second H-MRS were higher in the high-IS group in comparison with the low-IS group (frontal region, Glx/Cr, P = 0.04, Glx/H2O, P = 0.029; temporal region, Glx/Cr, P = 0.057, NS, Glx/H2O, P = 0.032) (Tables 2 and 3).
Sleep was deprived during the second 24 h.
Plasma samples were collected during the second 24 h of therapy.
Core body temperature is monitored continuously using an oesophageal probe and recorded every 4 h during the first 48 h after randomisation.
In intensive care, BGLs were controlled every 3 h during the first 12 h after arrival.
Patients aged ≥ 18 years old requiring ventilatory support for > 24 h during the first 48 h of ICU admission at the participating ICUs were included in the study.
Arterial blood was sampled every 1 h during the first 6 12 h after surgery, with capillary blood samples obtained by finger stick thereafter.
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