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Microdialysis studies in normal rats demonstrated increased prefrontal dopamine release during the incentive phase of behavior in an experimental situation specifically designed to evidence this behavioral aspect: the so called "sensory-specific satiety" procedure.
This is supported by the programme's descriptive data, which show an increase in contact time and the number of home visits during the incentive intervention.
Table 3 provides the location of peak voxels for all functional clusters observed in a priori anatomical regions demonstrating significant modulation across time during the incentive cue epoch.
For each PCT, percentage point change in chlamydia screening coverage and positivity for the period before and during the incentive was calculated.
For each PCT, we calculated the percentage point change in chlamydia screening coverage and positivity in the period before and during the incentive.
Most notably, adolescents, compared with adults, demonstrated attenuated responses in the VS during the incentive cue, followed by a heightened response in the VS and sPCS during response preparation (reward anticipation) on reward trials.
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For transient patterns, the contrasts involved the GLM estimates for the different trial types, averaged across time-points 2 6, which captures the period during which the incentive cue is presented and task performed (after accounting for the approximate 3 6 second hemodynamic lag), but likely minimizes effects related to reward feedback.
The cognitive component comprises an evaluation process during which the incentive value of a stimulus is appraised and attention is directed to it.
Given the impairment seen in alcoholic patients in the task, which were further exacerbated by multiple withdrawals, we asked whether those brain regions identified during imaging the incentive conflict task might be differentially compromised in MDTx patients.
There was no imaging of alcoholics during performance in the incentive conflict task, so we cannot be certain whether their impaired performance was accompanied by failure to activate appropriate brain regions or whether performance was impaired despite their activation.
None of the oculomotor control ROIs examined showed a significant age by time, incentive by time, or age by incentive by time interaction across the 13 estimated time points during the presentation of the incentive cue.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com