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Five (25%) patients received rhG-CSF during study treatment.
The best response during study treatment was reported.
No interruptions > 4 days between during study treatment are allowed.
Besides skin toxicity, 18.9% of the pts experienced other grade III/IV toxicities during study treatment.
The most common toxicities observed during study treatment are shown in Table 2.
Importantly, increased daily DCI during study treatment was not independently associated with decreased mortality.
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Treatment responses were assessed every three cycles (9 weeks) during study treatments or sooner if needed for documentation of disease progression.
In total, 21 (55.3%) patients died during the study (four patients during the study treatment period and 17 patients during follow-up).
Patients completed a daily paper diary during the study treatment period, in which they recorded heartburn severity during the past 24 hours.
- Adverse events will be reported during the study treatment phase.
Study participants were not engaged in individual or group psychotherapy during the study treatment time period.
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