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Cell detachment can occur during rearrangement; a detached cell reverts to the non-clustered state.
Deletion could also appeared during rearrangement.
Note that alternative PGD and WGD scenarios can be proposed in which duplications and deletions are allowed to occur at different times during rearrangement.
Strikingly, most of the TCRs used a Jβ2.6 segment that was truncated during rearrangement at its N-terminus precisely at the tyrosine residue.
This conservation was archived by a greater deletion at the 5'end of TRBJ genes and a concomitant increase in N-nucleotide addition at the V-D-J junction during rearrangement (fig. 2).
This observation suggested that this replication origin was recruited into this region in H. hispanica or was lost in H. marismortui during rearrangement of minichromosomes in the two Haloarcula species.
Similar(50)
It is likely that each RS domain interacts with U1-70K differentiatly at different stages of splicing and may be important during the rearrangement of spliceosomes during splicing.
Double-strand breaks (in one-half of the gene pair) are routinely generated during immunoglobulin gene rearrangement during normal lymphocyte maturation.
TRECs are generated during TCR rearrangement, are not replicated, and are diluted during subsequent cell divisions [ 8, 9].
It is during the rearrangement of his homeroom seating and acquaintance with Sekai Saionji, however, that Makoto's life begins to change.
These steps could be associated with the expression onset of specific proteins or factors responsible for different types of reactions during DNA rearrangement [40].
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